How Does ITP Impact Daily Life?
Living with ITP can take a toll on your daily life
For many, ITP changes how life feels day to day. It can show up in ways that aren’t always visible and aren’t always easy to explain.
In a large global survey, over 1500 people reported how ITP impacts different parts of their daily lives*:
85% felt reduced energy levels
Feeling less energetic than usual can affect both physical and emotional health, making even simple activities feel like a challenge.
75% had limited ability to complete daily tasks
When daily tasks seem challenging or take more effort, it can be frustrating, slow things down, and affect routine.
73% had difficulty concentrating
Sometimes known as brain fog, this can affect focus, memory, the ability to think clearly, and even staying organized or on track.
53% had anxiety about platelets
Worrying about staying in range can add to daily stress and uncertainty about what to expect.
50% had ITP-related fatigue
Fatigue is not the same as feeling tired. It’s ongoing, persistent exhaustion that doesn’t let up, even with a good night's sleep.
36% experienced loss of productivity
Finding it hard to get things done can be disruptive and discouraging, affecting responsibilities in both work and personal life.
*Data cited from the ITP World Impact Survey (I-WISh), a global cross-sectional study of 1507 patients and 472 physicians assessing the impact of ITP on quality of life and daily functioning.
“People living with ITP are so much more than our numbers.”
—Leigh Anne, living with ITP and taking WAYRILZ
In paid partnership with Sanofi. Individual results may vary.

Even when platelet counts improve, the effects of ITP may still be felt in everyday life
For many, treatment can feel like a cycle: trying to raise platelet counts, adjusting your approach, and trying again if levels fall. Even if treatment moves platelet counts into a safer range, people may still experience symptoms that impact their daily lives.
When thinking about treatment, it may help to consider the full impact of ITP to help guide your next steps.
WAYRILZ is a prescription medicine that is used to treat adults with persistent or chronic immune thrombocytopenia (ITP) who received a prior treatment that did not work well enough.
It is not known if WAYRILZ is safe and effective in children.
What should I tell my healthcare provider before taking WAYRILZ?
Tell your healthcare provider about all of your medical conditions, including if you:
- have liver problems
- have kidney problems
- are pregnant or plan to become pregnant. WAYRILZ may harm your unborn baby. If you are able to have a baby, your healthcare provider will do a pregnancy test before starting treatment with WAYRILZ. Females who are able to become pregnant should use an effective birth control during treatment with WAYRILZ and for 1 week after the last dose.
- are breastfeeding or plan to breastfeed. Do not breastfeed during treatment with WAYRILZ and for at least 1 week after the last dose.
Tell your healthcare provider about all the medicines you take, including prescription and over‑the‑counter medicines, vitamins, and herbal supplements. Taking WAYRILZ with certain other medicines may affect how WAYRILZ works and can cause side effects. WAYRILZ may also affect how other medicines work.
What should I avoid while taking WAYRILZ?
You should avoid grapefruit, starfruit and products that have these fruits, and Seville oranges (often used in marmalades) during treatment with WAYRILZ. These products may increase the amount of WAYRILZ in your blood, which increases the risk of side effects of WAYRILZ.
What are the possible side effects of WAYRILZ?
WAYRILZ may cause serious side effects, including:
- Serious infections. WAYRILZ can increase the risk of infections, including serious infections that can lead to death. Your healthcare provider will check you for signs and symptoms of infection during your treatment with WAYRILZ. Tell your healthcare provider right away if you get any signs or symptoms of infection, including fever, chills, or flu-like symptoms.
- Liver problems including Drug-Induced Liver Injury (DILI). Liver problems, which may be severe, life-threatening, or lead to death have happened in people treated with Bruton’s tyrosine kinase (BTK) inhibitors. Your healthcare provider will do blood tests to check your liver before and as necessary during treatment with WAYRILZ. Tell your healthcare provider right away if you have any signs or symptoms of liver problems, including stomach-area (abdominal) pain or discomfort, dark or “tea-colored” urine, or yellowing of the skin or the white part of your eyes.
The most common side effects of WAYRILZ include diarrhea, nausea, headache, stomach area (abdominal) pain, and COVID-19.
These are not all of the possible side effects of WAYRILZ.
Please see full Prescribing Information, including Patient Information.
