Frequently Asked Questions
ABOUT ITP
Immune thrombocytopenia (ITP) is a rare autoimmune disorder in which your body mistakenly attacks its own platelets.
The result is the symptoms you experience, such as bleeding, bruising, and other impacts on your daily life.
- Easy bruising or bruises without a clear cause
- Red or purple pinpoint spots on arms and legs (petechiae)
- Frequent or prolonged bleeding (like heavy periods in women, bleeding gums or nosebleeds)
- ITP may also impact aspects of your daily life, such as your energy levels, fatigue, and mood
No. ITP can look different person to person. Talk to your doctor about all the possible symptoms you are experiencing and whether they could be related to ITP.
Yes. Even when your platelet count is stable, ITP can still affect how you feel—physically and emotionally. Fatigue, anxiety about platelet counts, and limited ability to complete daily tasks are common for many people living with ITP.
ABOUT WAYRILZ
WAYRILZ helped adults with persistent or chronic ITP who have received a prior treatment that did not work well enough.
Of course, your results may vary.
Use this short symptoms and goals snapshot tool and receive a guide that can help support the conversation with your doctor to find out if WAYRILZ is right for you.
WAYRILZ is an FDA-approved treatment for adults with persistent or chronic ITP that improves and sustains platelet counts. 23% of people taking WAYRILZ reached and maintained target platelet counts vs 0% not taking WAYRILZ.
During the last 12 weeks of the study, people reached a platelet level of 50,000 or higher more than 5 times when measured weekly, without rescue therapy, including at least twice in the final 6 weeks.
Learn about WAYRILZ clinical study results
Many treatments for ITP focus primarily on increasing platelet production.
WAYRILZ targets key sources of ITP to help stop platelet destruction and restore immune balance.
No, WAYRILZ is not a steroid. It is designed to target key sources of ITP and helps to restore immune balance.
WAYRILZ is one pill you take twice a day, with or without food. It can conveniently fit into your schedule because there are no infusions and no injections.
You should avoid grapefruit, starfruit and products that have these fruits, and Seville oranges (often used in marmalades) while taking WAYRILZ. These products may increase the amount of WAYRILZ in your blood, which increases the risk of side effects of WAYRILZ.
Tell your healthcare provider about all the medicines you take, including prescription and over‑the‑counter medicines, vitamins, and herbal supplements. Taking WAYRILZ with certain other medicines may affect how WAYRILZ works and can cause side effects. WAYRILZ may also affect how other medicines work.
Please tell your doctor if you are taking medications for heartburn, acid reflux, or ulcers, such as antacids, H2 (histamine-2) blockers, or proton pump inhibitors (PPls), as these may require additional instructions.
If you miss a dose, take it as soon as possible on the same day and return to your regular schedule the following day. The missed dose and next regular scheduled dose must be taken more than 2 hours apart. Do not take an extra dose to make up for a missed dose.
Take WAYRILZ exactly as your healthcare provider tells you to take it. Do not change your dose or stop taking WAYRILZ unless your healthcare provider tells you to.
The most common side effects of WAYRILZ include:
- diarrhea
- nausea
- headache
- stomach area (abdominal) pain
- COVID-19
These are not all of the possible side effects of WAYRILZ. Call your doctor for medical advice, including tips on managing potential side effects. You may report side effects to the FDA at 1-800-FDA-1088.
You can start by getting your own personalized guide on this website. Answer a few questions about how ITP affects you, as well as your treatment goals. This may help you have a more productive conversation with your doctor when discussing if WAYRILZ could be a good option for you.
Yes.
Because it’s an oral treatment, WAYRILZ is easy to take with you—no refrigeration or special handling are needed. WAYRILZ should be kept at room temperature in the original packaging. Protect WAYRILZ from light and moisture.
Once you're prescribed WAYRILZ, HemAssist™ Patient Support from Sanofi is there for you. This program will help you with access to WAYRILZ, financial assistance, and education throughout your treatment journey.
Every person's situation is different, which is why we work directly with you to help simplify the financial assistance program for which you may be eligible.
WAYRILZ is a prescription medicine that is used to treat adults with persistent or chronic immune thrombocytopenia (ITP) who received a prior treatment that did not work well enough.
It is not known if WAYRILZ is safe and effective in children.
What should I tell my healthcare provider before taking WAYRILZ?
Tell your healthcare provider about all of your medical conditions, including if you:
- have liver problems
- have kidney problems
- are pregnant or plan to become pregnant. WAYRILZ may harm your unborn baby. If you are able to have a baby, your healthcare provider will do a pregnancy test before starting treatment with WAYRILZ. Females who are able to become pregnant should use an effective birth control during treatment with WAYRILZ and for 1 week after the last dose.
- are breastfeeding or plan to breastfeed. Do not breastfeed during treatment with WAYRILZ and for at least 1 week after the last dose.
Tell your healthcare provider about all the medicines you take, including prescription and over‑the‑counter medicines, vitamins, and herbal supplements. Taking WAYRILZ with certain other medicines may affect how WAYRILZ works and can cause side effects. WAYRILZ may also affect how other medicines work.
What should I avoid while taking WAYRILZ?
You should avoid grapefruit, starfruit and products that have these fruits, and Seville oranges (often used in marmalades) during treatment with WAYRILZ. These products may increase the amount of WAYRILZ in your blood, which increases the risk of side effects of WAYRILZ.
What are the possible side effects of WAYRILZ?
WAYRILZ may cause serious side effects, including:
- Serious infections. WAYRILZ can increase the risk of infections, including serious infections that can lead to death. Your healthcare provider will check you for signs and symptoms of infection during your treatment with WAYRILZ. Tell your healthcare provider right away if you get any signs or symptoms of infection, including fever, chills, or flu-like symptoms.
- Liver problems including Drug-Induced Liver Injury (DILI). Liver problems, which may be severe, life-threatening, or lead to death have happened in people treated with Bruton’s tyrosine kinase (BTK) inhibitors. Your healthcare provider will do blood tests to check your liver before and as necessary during treatment with WAYRILZ. Tell your healthcare provider right away if you have any signs or symptoms of liver problems, including stomach-area (abdominal) pain or discomfort, dark or “tea-colored” urine, or yellowing of the skin or the white part of your eyes.
The most common side effects of WAYRILZ include diarrhea, nausea, headache, stomach area (abdominal) pain, and COVID-19.
These are not all of the possible side effects of WAYRILZ.
Please see full Prescribing Information, including Patient Information.
